15 Vesicles: Formation, Fusion And Proteins (incl. retrograde and anterograde transport)

In this BioSpeak episode, we unravel the intricate process of vesicle formation, focusing on endocytosis, anterograde, and retrograde transports between the ER and Golgi apparatus. Highlighting a protein entourage, we explore the formation steps involving adaptin, clathrin, and dynamin, crucial in creating vesicles and shedding the clathrin coat before transport. Delving into retrograde and anterograde transports, we meet VIP proteins COP1 and COP2, unveiling their distinctive roles in coat assembly and cargo release. The episode dives deeper into vesicle docking and fusion, spotlighting Rab-GTPase, Rab effectors, and SNARE proteins orchestrating a remarkable protein dance culminating in cargo release. Join us on this riveting biological journey, leaving us with questions or revelations, and stay tuned for our next exploration into the wonders of life! Connect with us at biospeakcast@gmail.com